You could always ask over at Nintendo Age. Those guys can give you a much better reply than just about anyone else on the internet.

Noooo! It's factory-sealed (at least that is the seller's claim) (in fact, EB was never shrink-wrapped; I believe it had those clear plastic stickers on the side edges where the flaps open).

What Onion was talking about when he said "sealed by the VGA" is the hard plastic box that they put the game in when they grade it and return it to you.